First step was to communicate with the GM65 barcode reader.  A Wemos can not read from USB, so i had to use UART.  I used the Arduino library softSerial to read data from the UART bus. 

https://www.arduino.cc/en/Reference/softwareSerial

When a barcode is scanned it will send the value to a remote server over a SSL connection.  I used a Linux based webserver with Apache2 , MySQL and PHP.