So I'm starting to get an idea of what I want to do.  Here is a more filled in picture of my garage.  The grey boxes are storage cabinets and shelves that I already have. I could move them, but it would be best if they stayed right where they are.

The yellow box is a movable freezer, I could put it in several places, but for now this seems like the right place.  The yellow drill press is also movable, I have not settled on a final place for it.

My first idea is to add in shelves about 20" from the top of the ceiling all around the room. That will let me move some existing boxes up and out of the way so we have more room to work with.  In addition I would like to build in a storage solution next to the existing ones by the washer and dryer.  There is some space on the wall that is not being put to good use and this would nicely fill it out.

This has one issue, I already have some bikes and a ladder hanging from the roof.  I will need to come up with a plan for both of those.  The bikes have not been used in years, but the ladder is the only way to get to the roof.

Once we have freed up space then this is my rough idea for the actual shop area. First off you can see that we don't have a lot of room to work with.  We need a minimum amount of space next to the drivers side of each car in order to be able to pull them in and out of the garage.  We also need to leave some clearance around the ac/heater as well as leave a path into the house and a space to use the machines.  That leaves a small space at the lower right side of the image below to store all the tools and tables.

So the idea here is the larger purple square would be a work bench with built in storage.  This would be on wheels and easily rolled out if I need to do serious work.  The smaller purple square would be my CNC with all the storage needed for the various parts, as well as some air filtration and so on.  The stand alone orange square would have my chop saw on top of it.  And the other orange box would be some additional storage that wraps around the base of the drill press.