Code to find device

import usb.core
dev = usb.core.find(idVendor=0x03eb, idProduct=0x2402)
print dev

Control Endpoint Read (Slide 94)

import usb.core
dev = usb.core.find(idVendor=0x03eb, idProduct=0x2402)
dev.set_configuration()

data = dev.ctrl_transfer(0b10100001, 0x01, 3<<8, 0, 4)

print data

Sending Output Report

import usb.core
dev = usb.core.find(idVendor=0x03eb, idProduct=0x2402)
print dev

dev.set_configuration()

data = [ord('1'), ord('1'), 0, 0, 0, 0, 0, 0]
dev.write(0x02, data)

Getting Input Report (Press "user" button for things to happen)

import usb.core
dev = usb.core.find(idVendor=0x03eb, idProduct=0x2402)
print dev

dev.set_configuration()

for i in range(0, 10):
    while True:
        try:
            test = dev.read(0x81, 8, timeout=50)
            break
        except usb.core.USBError, e:            
            if str(e).find("timeout") >= 0:
                pass
            else:
                raise IOError("USB Error: %s"%str(e))
     
    print test

Full-on GUI

#Public domain - simple USB GUI Example by Colin O'Flynn

from PySide.QtCore import *
from PySide.QtGui import *
import usb.core
import sys

class USBForm(QDialog):
    def __init__(self, parent=None):
        super(USBForm, self).__init__(parent)
        self.setWindowTitle("SuperCon 2015 Demo")

        layout = QVBoxLayout()
        self.setLayout(layout)

        self.pbConnect = QPushButton("Connect")
        self.pbConnect.clicked.connect(self.con)
        self.isConnected = False

        self.pbLED = QPushButton("LED Blinking")
        self.pbLED.setCheckable(True)
        self.pbLED.clicked.connect(self.changeLED)
        self.pbLED.setEnabled(False)

        layout.addWidget(self.pbConnect)
        layout.addWidget(self.pbLED)

        self.swStatus = QLineEdit()
        self.swStatus.setReadOnly(True)
        layout.addWidget(self.swStatus)

        self.butTimer = QTimer(self)
        self.butTimer.timeout.connect(self.pollButton)


    def con(self):
        if self.isConnected == False:
            #Do USB Connect Here
            self.dev = usb.core.find(idVendor=0x03eb, idProduct=0x2402)
            self.dev.set_configuration()

            #Sync changeLED
            self.changeLED()
            
            self.isConnected = True
            self.pbConnect.setText("Disconnect")
            self.pbLED.setEnabled(True)
            self.butTimer.start(100)
        else:
            self.isConnected = False
            self.pbConnect.setText("Connect")
            self.pbLED.setEnabled(False)
            self.butTimer.stop()

    def changeLED(self):
        if self.pbLED.isChecked():
            #Send command to make LED on
            self.dev.write(0x02, [ord('1'), ord('1'), 0, 0, 0, 0, 0, 0])

            self.pbLED.setText("LED On")            
        else:
            #Send command to make LED blink
            self.dev.write(0x02, [ord('0'), ord('1'), 0, 0, 0, 0, 0, 0])
            self.pbLED.setText("LED Blinking")

    def pollButton(self):
        try:
            data = self.dev.read(0x81, 8, timeout=50)
            if data[0]:
                self.swStatus.setText("Button Pressed")
            else:
                self.swStatus.setText("Button Released")
                
        except usb.core.USBError, e:
            if str(e).find("timeout") >= 0:
                pass
            else:
                raise IOError("USB Error: %s"%str(e))


if __name__ == "__main__":
    app = QApplication(sys.argv)
    form = USBForm()
    form.show()
    sys.exit(app.exec_())